Major Shareholders

Shares in Issue: 472,716,142 p Ords
Last updated: 10 March 2017

Major Shareholders Amount % Holding
MVM Life Science Partners 55,561,900 11.75
Fidelity Management & Research 44,322,946 9.38
Aviva Investors 41,473,495 8.77
Nigel Wray 36,385,905 7.70
Slater Investments 35,630,000 7.54
ArtemisFund Mgrs Ltd 34,355,611 7.27
River & Mercantile Asset Management 23,550,000 4.98
John Dawson (beneficial) 21,000,079 4.44
John Dawson (non beneficial) 20,000,000 4.23
Stella Dawson 15,576,323 3.29
Shareholdings of Directors & their families Amount % Holding
John Dawson (beneficial) 39,576,402 7.74
John Dawson (non beneficial) 20,000,000 4.23
Andrew Smith 275,000 0.06
Nigel Clifford 180,663 0.04
David Cook 102,371 0.02
Peter Butterfield 28,376 0.01